Functional visual responses were significantly more preserved in mice under the filter than in unprotected mice
The structure of the retina was more preserved in the experimental group and the number of photoreceptors did not decrease significantly compared to the control group exposed to light without a protective filter. The results of the research show that the waves from the electroretinogram were reduced by up to 90% in the unprotected mice, but only by 40% in the protected group. This demonstrates that the blue-blocking filter was able to significantly protect the retina from the harmful effects of exposure to light with a high-intensity blue component.
The number of photoreceptor nuclei in the outer nuclear layer (ONL) was significantly higher in the protected group than in the unprotected group, especially in the central retinal regions
The research confirmed that the blue-blocking filter helped preserve the structural integrity of the photoreceptors. In addition, photoreceptor morphology was better preserved in the protected group, and cone outer segments and rod outer segments were more intact compared with the unprotected group. This further demonstrates the protective effect of the blue-blocking filter against light-induced retinal damage.
