The phototoxicity of full spectrum LEDs is less than that of standard LEDs, even at high luminance, and standard LEDs can induce ER stress even at low intensity (300 lx)
Blue light is associated with eye fatigue, dry eye syndrome, colour blindness, photoreceptor degeneration and retinal damage. The damage caused by full-spectrum LEDs was significantly attenuated compared to standard LEDs, which increased the expression of S-opsin and biochemical markers indicating ongoing ER stress.
Full-spectrum LED lighting reduces light-induced retinal degeneration through ER stress control
The study authors concluded that standard cold LEDs can induce ER stress and protein response in light-induced retinal degeneration (LIRD), while full-spectrum LEDs can alleviate LIRD by regulating ER stress in the retina.
