Study

A UK study shows that exposure to 670 nm light in the morning significantly improves sensitivity to colour contrast in the ageing population.

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Title:

Weeklong improved color contrasts sensitivity after single 670 nm exposures associated

Author: Harpreet Shinhmar, Chris Hogg, Magella Neveu & Glen Jeffery Biotechnology and Biological Sciences Research Council UK (BB/N000250/1) and the National Eye Research Centre UK.
Date: 21. November 2021
Source: https://doi.org/10.1038/s41598-021-02311-1
PDF: Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated.PDF

Brief summary

Exposure to light with longer wavelengths (650-900 nm) for several weeks improved mitochondrial function and ATP production, which decrease with age. This study builds on existing knowledge and demonstrated that a single three-minute exposure to 670 nm light in the morning at lower energy levels was enough to significantly improve the color contrast perception threshold mediated by cones in the aging population (37-70 years) to the level of a younger population within a week. This implies that this intervention can significantly improve color vision in old age. Importantly, beneficial effects were observed only with morning exposure to light, indicating the time-dependent sensitivity of fundamental mitochondrial processes. These findings suggest a simple and effective way to improve visual functions in the aging population.

Studies show that exposure to long wavelengths (650-900 nm) for several weeks partially restores ATP and improves mitochondrial function.

The mitochondrial membrane potential decreases with age, leading to reduced production of adenosine triphosphate (ATP), the main source of cellular energy. Cell loss with ageing is further accelerated by increased production of pro-inflammatory reactive oxygen species (ROS). However, studies show that exposure to long wavelengths (650-900 nm) for several weeks improves mitochondrial function, increases ATP production and reduces ROS.

Brief morning exposure to 670 nm red light resulted in a significant improvement in colour contrast sensitivity

The colour contrast sensitivity was assessed through the tritan (blue-yellow) and protan (red-green) colour axes. The results showed that on the tritan axis, there was an average reduction in threshold (i.e., increase in sensitivity) of 17% in both men and women. On the protan axis, the improvement was more modest – 10% in men and 14% in women. The highest improvement on the tritan axis was observed in people over 50 years of age – around 20%. The improvement on the protan axis was slightly more even across age groups – around 12%. The improvement in colour contrast sensitivity persisted even one week after a single exposure. This suggests that red light has a more lasting effect on retinal function, and shows the potential of red light as a non-invasive way to promote sensitivity to colour contrasts, particularly in older age.

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